Adverse impacts of the Trans Pacific Partnership on public health have been well documented but how might the pact affect regional and global economies? A new report “Trading Down: Unemployment, Inequality and Other Risks of the Trans-Pacific Partnership Agreement,” on the Trans Pacific Partnership by investigators at Tufts University asks that question. It concludes that “the benefits to economic growth are even smaller than those projected with full-employment models, and are negative for Japan and the United States. More important, we find that the TPP will likely lead to losses in employment and increases in inequality.”